Pothos is very easy to grow. It prefers bright, indirect light but is even able to survive for long periods in low light. Mist the leaves regularly to keep humidity levels up and let the well-drained potting medium dry out between waterings. Fertilize every other month except when the plant is dormant in the winter. Wipe down the leaves every so often with a soft rag to remove any collected dust. Over time leaves will yellow and fall off, concentrating most of the leaves at the end of the stems. Prune stems back to maintain a bushy habit. Vines easily root in water. They climb by brown adhesive aerial roots. If given a support on which to climb and adequate light, the plant will begin to produce large, mature leaves.